Publications by authors named "S Q Ka"

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus causing fever, myalgia, and debilitating joint swelling and pain, which in many patients becomes chronic. The frequent epidemics of CHIKV across the world pose a significant public health burden necessitating the development of effective antiviral therapeutics. A cellular imaging-based high-content screening of natural compounds identified withaferin A (WFA), a steroidal lactone isolated from the plant Withania somnifera, as a potent antiviral against CHIKV.

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Article Synopsis
  • There is a significant lack of surgical capabilities to manage the increasing cancer care needs in West Africa, prompting the proposal for a surgical oncology fellowship training program.
  • A comprehensive needs assessment was conducted using a mixed-methods approach, including surveys and site visits at eight leading cancer centers to evaluate current capabilities and educational needs.
  • The findings, which included a SWOT analysis, revealed the existing clinical resources and developed a list of essential surgical procedures necessary for training, serving as a foundation for creating the fellowship program.
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Article Synopsis
  • Low- and middle-income countries (LMICs), especially in West Africa, struggle with limited surgical capacity to address the increasing need for cancer care, primarily managed by general surgeons without specialized training.
  • The West African College of Surgeons (WACS) teamed up with the Global Oncology Group at Queen's University to create a tailored surgical oncology fellowship program by reviewing existing literature and seeking input on regional competencies.
  • The newly developed curriculum focuses on essential knowledge and skills in surgical oncology, outlining educational activities and assessment methods, aiming to improve cancer surgery capacity in West Africa and potentially serve as a model for other LMICs.
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