Adaptation to recent conflict in the classical color-word Stroop-task mainly involves facilitation of processing of task-relevant information.

To process information selectively and to continuously fine-tune selectivity of information processing are important abilities for successful goal-directed behavior. One phenomenon thought to represent this fine-tuning are conflict adaptation effects in interference tasks, i.e.

Attentional adjustment to conflict strength: evidence from the effects of manipulating flanker-target SOA on response times and prestimulus pupil size.

Current models of cognitive control assume gradual adjustment of processing selectivity to the strength of conflict evoked by distractor stimuli. Using a flanker task, we varied conflict strength by manipulating target and distractor onset. Replicating previous findings, flanker interference effects were larger on trials associated with advance presentation of the flankers compared to simultaneous presentation.

Adjustments to recent and frequent conflict reflect two distinguishable mechanisms.

In conflict paradigms such as the Eriksen flanker task, interference has been found to be reduced under conditions of recent and/or frequent cognitive conflict. Using a modified flanker task, we investigated the interplay of conflict recency and conflict frequency by comparing the interference reductions following conflict trials under conditions in which conflict was either frequent or infrequent overall, while controlling for stimulus and response feature repetitions to rule out nonattentional accounts. The reduction of flanker interference after a conflict trial was attenuated when overall conflict was frequent.

Clinical features of maternal uniparental disomy 14 in patients with an epimutation and a deletion of the imprinted DLK1/GTL2 gene cluster.

Maternal uniparental disomy 14 [upd(14)mat] is associated with a recognizable phenotype that includes pre- and postnatal growth retardation, neonatal hypotonia, feeding problems and precocious puberty. Chromosome 14 contains an imprinted gene cluster, which is regulated by a differentially methylated region (IG-DMR) between DLK1 and GTL2. Here we report on four patients with clinical features of upd(14)mat who show a maternal-only methylation pattern, but biparental inheritance for chromosome 14.