Publications by authors named "S Pulini"
Article Synopsis
- * The patient underwent a treatment regimen involving daratumumab, bortezomib, thalidomide, and dexamethasone, followed by stem-cell collection and autologous stem cell transplantation (ASCT).
- * The combination treatment showed promising effectiveness for managing both cancers, with successful stem cell mobilization and quick recovery post-transplant, despite initial concerns regarding the management of these complex conditions.
Background: In combination with dexamethasone, lenalidomide is prescribed in the oral treatment of Multiple Myeloma for patients who have received at least one previous therapy.
Objective: The objective of this study is to evaluate medication adherence to lenalidomide of Multiple Myeloma patients, as well as Progression Free Survival and Overall Survival one year from the beginning of the treatment.
Setting: The study was carried out in Pescara Hospital, in Italy.
We conducted a pooled analysis of two phase III trials, RV-MM-EMN-441 and EMN01, to compare maintenance with lenalidomide-prednisone vs. lenalidomide in newly diagnosed transplant-eligible and -ineligible myeloma patients. Primary endpoints were progression-free survival, progression-free survival 2 and overall survival with both regimens.
View Article and Find Full Text PDF