Enhanced Adsorption and Photocatalytic Removal of Cationic Dyes in Aqueous Solutions by Ternary Graphene Oxide-TiO₂-SiO₂ Nanocomposites.

In this study, adsorption is an attractive for the removal of industrial dyes from aqueous simulated wastewaters is reported. The ternary graphene oxide-TiO₂-SiO₂ (GTS) nanocomposite was synthesized by sol-gel method. The as-synthesized nanocomposite was characterized by XRD, BET, FT-IR, SEM-EDAX and TEM analysis.

Carbon nanoparticle from a natural source fabricated for folate receptor targeting, imaging and drug delivery application in A549 lung cancer cells.

There is an emerging need for the development of new anticancer nanocomposite which exhibits imaging properties and targeted drug delivery. In the present study, a nanobiocomposite was prepared, in this direction, which contains carbon nanoparticles (CNP), methotrexate (Mtx) and asparaginase (Asp) coupled with fluorescein isothiocyanate (FITC). The prepared nanobiocomposite kills only the cancer cells due to the presence of Mtx which is a folic acid analogue and targets the cancer cells due to the over expression of folate receptors on their surface and apoptosis occurs due to the anticancer activity of enzyme asparaginase.

Bio-modified carbon nanoparticles loaded with methotrexate possible carrier for anticancer drug delivery.

The modification of carbon nanoparticles (CNPs) using biological molecules is important in the field of chemical biology, as the CNPs have the potential to deliver the drugs directly to the targeted cells and tissues. We have modified the CNPs by coating bovine serum albumin (BSA) on their surfaces and loaded with methotrexate (Mtx). Infrared spectra have revealed the coating of BSA and Mtx on CNP (CBM).

Phylogenetic conservation of the stem-loop III structure of the 5' untranslated region of Hepatitis C virus RNA among natural variants in samples collected from Southern India.

The stem-loop III (SLIII) structure within the 5' untranslated region has been shown to be critical for internal initiation of translation of Hepatitis C virus (HCV). Using 'Single Strand Conformation Polymorphism (SSCP)' of the SLIII region we have investigated for natural mutations and demonstrated presence of some non-covariant changes in certain sub-domains. However, overall SLIII-RNA structure was found to be phylogenetically conserved.