Publications by authors named "S Pratesi"
Background: The issue of retreatment with surfactant of infants with respiratory distress syndrome (RDS) has been poorly investigated. Our aim was to identify possible clinical predictors of the need for multiple doses of surfactant in a large cohort of very preterm infants.
Methods: Data were analyzed from three previous studies on infants born between 25 and 31 weeks of gestation with RDS who were treated with surfactant.
Importance: Among preterm newborns undergoing resuscitation, delayed cord clamping for 60 seconds is associated with reduced mortality compared with early clamping. However, the effects of longer durations of cord clamping with respiratory support are unknown.
Objective: To determine whether resuscitating preterm newborns while keeping the placental circulation intact and clamping the cord after a long delay would improve outcomes compared with umbilical cord milking.
Article Synopsis
- The study investigated the effectiveness of multiple drug treatments using ibuprofen and/or paracetamol for closing or constricting hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants with gestational ages under 29 weeks.
- Results showed a significant increase in treatment failure rates: 38% for the first course, 76% for the second, and 92% for the third.
- The findings suggest that repeating drug treatments may expose very preterm infants to prolonged risks associated with hsPDA, as many required surgical intervention or experienced adverse outcomes.
Systemic sclerosis is considered a rare autoimmune disease in which there are alterations of both the innate and adaptive immune response resulting in the production of autoantibodies. Abnormalities of the immune system compromise the normal function of blood vessels leading to a vasculopathy manifested by Raynaud's phenomenon, an early sign of systemic sclerosis. As a consequence of this reactive picture, the disease can evolve leading to tissue fibrosis.
View Article and Find Full Text PDFCyclic phototherapy (cPT) can achieve a reduction in total serum bilirubin comparable to that achieved with standard continuous PT in preterm infants. Our aim was to assess the effect of cPT on splanchnic (rSOS) and cerebral (rSOC) oxygenation measured by near-infrared spectroscopy (NIRS). We prospectively studied 16 infants with a gestational age of 25-34 weeks with hyperbilirubinemia requiring PT.
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