Publications by authors named "S Prabhudesai"
Primary cilia from the brain microvascular endothelial cells (ECs) are specialized cell-surface organelles involved in mediating sensory perception, cell signaling, and vascular stability. Immunofluorescence (IF) analysis of human primary brain microvascular ECs reveals two cilia per cell. To confirm the observation of the two-cilia phenotype in human primary brain ECs, ECs isolated from mouse brain were cultured and stained for cilium.
View Article and Find Full Text PDFElastin remodeling: Does it play a role in priming the malignant phenotype of oral mucosa?
Indian J Pathol Microbiol
April 2023
Background: The extracellular matrix (ECM) is a dynamic tissue that provides nutrition and support to overlying epithelium. During tumorigenesis, the tumor microenvironment (TME) dysregulates the ECM. This is reflected by morphological changes seen in collagen and elastic fibers and is thought to facilitate metastasis.
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- Machine learning can work well, but it often struggles to make accurate predictions on new data, which is called out-of-sample generalizability.
- To solve this problem, researchers are using a method called Federated ML that allows computers to share information about how well they're learning without actually sharing the data itself.
- In a big study with 71 locations around the world, scientists created a model to help detect brain tumors more accurately, showing a significant improvement compared to older methods and hoping to help with rare illnesses and data sharing in healthcare.
We describe a 3-month-old baby who presented with a nonresolving pneumonia which failed to respond to antibiotic therapy. An underlying congenital pulmonary adenomatous malformation was suspected. On thoracotomy, she was found to have a tuberculous mediastinal abscess which was drained.
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