Gallbladder adenomyoma/adenomyomatous nodule/adenomyomatosis is a benign condition characterized by mucosal invaginations within the gallbladder wall with or without proliferation of smooth muscle fibers. Gallbladder adenomyoma is often asymptomatic and discovered incidentally during imaging studies performed for other unrelated conditions. It can mimic malignancy on radiological findings, creating a diagnostic dilemma.
View Article and Find Full Text PDFBickerstaff brain stem encephalitis (BBE) is a rare brainstem disorder characterized by acute onset of ophthalmoplegia, ataxia, and altered consciousness. Guillain Barre syndrome (GBS), Miller Fischer syndrome and BBE share certain similarities such as the presence of anti-ganglioside antibodies. The use of Therapeutic Plasma Exchange (TPE) has been reserved for severe to fulminant cases of BBE mostly as an 'off label' use.
View Article and Find Full Text PDFPrioritizing chemicals posing threats to drinking water resources is crucial for legislation considering the cost of water treatment, remediation, and monitoring. We profiled in vitro potential endocrine disrupting activities (both agonistic and antagonistic) of 18 contaminants most prevalent in Walloon raw water resources intended for drinking water production, including several compound groups: pesticides, perfluorinated compounds, polycyclic aromatic hydrocarbons, a corrosion inhibitor, and bisphenol A. Mixtures thereof relevant for human realistic exposure were also investigated.
View Article and Find Full Text PDFIntroduction: The protein kinase C (PKC) is a family of multifunctional isoenzymes involved in apoptosis, migration, adhesion, tumorgenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation. It also plays a vital role in the regulation of signal transduction, cell proliferation and differentiation through positive and negative regulation of the cell cycle. In this work, we reviewed the existing PKC inhibitors and several patents linked to PKC inhibitors.
View Article and Find Full Text PDFOne method for treating chronic incapacitating acromioclavicular dislocation is to resect the external extremity of the clavicle and to stabilise the stump by ligamentoplastic procedures, using the coracoclavicular ligament. The purpose of this work was to evaluate the mechanical quality of the ligamentoplastic approach. Twelve fresh cadavers, average age 80 years, were studied.
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