Acute effect of altered tryptophan levels and alcohol on aggression in normal human males.

Normal males received amino acid mixtures designed to raise or lower tryptophan availability, and thus to raise or lower brain serotonin synthesis. They also received alcoholic or non-alcoholic drinks. The subjects were tested in the Taylor Competitive Reaction Time Task in which they competed against a (non-existent) partner in a reaction time task.

A swinging heart in limited systemic sclerosis.

We describe a 3rd patient with limited cutaneous systemic sclerosis (ISSc) complicated by a pericardial effusion sufficient to cause hemodynamic compromise. Although more commonly appreciated as a complication of diffuse systemic sclerosis, the recognition of hemodynamically compromising pericardial effusion presenting in the limited form of ISSc can be lifesaving.