Publications by authors named "S Pilz"
Purpose: It has been assumed that magnesium (Mg) status may interact with vitamin D status. We therefore aimed at investigating the association between Mg and vitamin D status in a large cohort of adult individuals with a high prevalence of deficient/insufficient vitamin D and Mg status.
Methods: We used data from the Ludwigshafen Risk and Cardiovascular Health Study (n = 2,286) to analyze differences according to serum Mg status in circulating 25-hydroxyvitamin D [25(OH)D] (primary endpoint), 24,25-dihydroxyvitamin D [24,25(OH)D], vitamin D metabolite ratio and calcitriol, and odds ratios for deficient or insufficient 25(OH)D (secondary endpoints).
Denosumab is a potent antiresorptive medication, commonly used in the treatment of osteoporosis, as well as in a variety of other diseases. Potential adverse rebound effects after its cessation include a loss in bone mineral density and an increased risk of osteoporotic fractures. Hypercalcemia is a less frequently reported rebound phenomenon after denosumab discontinuation, that may pose a diagnostic challenge to physicians as a rare non-parathyroid hormone (PTH) dependent cause of hypercalcemia.
View Article and Find Full Text PDFBackground: We aimed to evaluate the effectiveness of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations in previously SARS-CoV-2-infected adults in the general population of Austria during the Delta wave and with extended follow-up.
Methods: In a nationwide retrospective cohort study, we calculated age-, sex-, and nursing home residency-adjusted Cox proportional hazard ratios (HRs) of coronavirus disease 2019 (COVID-19) deaths, SARS-CoV-2 infections, and non-COVID-19 deaths from 1 October to 31 December 2021, and secondarily with extended follow-up to 30 June 2022. Relative vaccine effectiveness (rVE) is rVE = (1 - HR) × 100.
Article Synopsis
- Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of ACTH-independent Cushing syndrome (CS) that complicates diagnosis due to its similarities with other conditions.* -
- A 22-year-old female exhibited classic symptoms like weight gain and moon facies, but imaging tests showed normal adrenal glands, making it difficult to find the source of cortisol overproduction.* -
- Ultimately, adrenal vein sampling confirmed cortisol came from the adrenal glands, leading to successful treatment through bilateral adrenalectomy and a diagnosis of PPNAD linked to a genetic mutation associated with the Carney complex.*
Article Synopsis
- * The main issue resulting from vitamin D toxicity is hypercalcemia, which can be difficult to treat and can stem from various causes, including genetic mutations and excessive intake.
- * The manuscript discusses possible treatments for vitamin D toxicity, highlighting the use of systemic corticosteroids as effective after traditional methods fail, as well as alternative options that could limit steroid side effects.