Metformin may decrease cell senescence, including bone; hence we aimed at evaluating the association between metformin use and osteoporosis. This was a cross-sectional study carried out in 1259 Latin American adult women aged 40 or more who were not on anti-osteoporotic drugs, were on metformin and had a bone densitometry performed. Of the whole sample, 40.
View Article and Find Full Text PDFSleep disorders (insomnia, hypersomnia, parasomnias and breathing disturbances), hormonal changes and vasomotor symptoms are highly prevalent in peri and postmenopausal women. The aim of our study was to assess sleep quality, some sleep disturbances, depression and suffocation during postmenopausal. Data come from a cross-sectional study of 195 women, which was conducted at a University Hospital.
View Article and Find Full Text PDFUnlabelled: Sleep disorders, resulting from hormonal changes and vasomotor symptoms, are common in both peri- and postmenopausal women. Poor sleep quality is associated with increased metabolic and cardiovascular risk, depression and a global impairment in health status.
Objectives: Our study aimed to assess sleep quality in a sample of postmenopausal women and to identify the factors associated with poor sleep quality.
Objective: To assess the effect of tibolone on endometrial safety, plasma estradiol concentrations, lipid metabolism and climacteric symptoms in comparison to sequential conjugated equine estrogens and medroxyprogesterone acetate in postmenopausal women.
Methods: In a randomised, open-label, 6-cycle, group-comparative study, the effects on the aforementioned parameters were studied with tibolone 2.5 mg/day (N = 13) continuously, and with conjugated equine estrogens 0.