Publications by authors named "S Piana"
Objective: This study aimed to understand the dynamics of including Pathologists' Assistants in a surgical pathology department.
Methods: A qualitative ethnographic study employed covert participant observation and semi-structured interviews. Field notes and interview transcripts were descriptively analysed to identify categories.
The advent of "omics" technologies for high-depth tumor profiling has provided new information regarding cancer heterogeneity. However, a bulk omics profile can only partially reproduce tumor complexity, and it does not meet the preferences of pathologists used to perform an in situ assessment of marker expression, for instance, with immunohistochemistry. The NanoString GeoMx® Digital Spatial Profiler (DSP) is a platform for morphology-guided multiplex profiling of tissue slides, which allows the digital quantification of target analytes in different neoplastic settings.
View Article and Find Full Text PDF: The impact of subpulmonary left ventricle (LV) dysfunction in patients with a systemic right ventricle (SRV) is insufficiently characterized, with only a few studies suggesting its prognostic significance. Additionally, its evaluation through imaging techniques is a challenge. To assess the correlation between quantitative cardiac magnetic resonance-feature tracking (CMR-FT) data and the risk of clinical events related to the natural history of SRV failure.
View Article and Find Full Text PDFGastric cancer (GC) is the second most common cause of cancer-related death worldwide and a serious public health concern. This high death rate is mostly caused by late-stage diagnoses, which lead to poor treatment outcomes. Radiation immunotherapy and targeted therapies are becoming increasingly popular in GC treatment, in addition to surgery and systemic chemotherapy.
View Article and Find Full Text PDFArticle Synopsis
- Systemic right ventricle (sRV) dysfunction is common in patients with congenitally corrected transposition of great arteries (cc-TGA) and dextro-transposition of great arteries (D-TGA) post-surgery, highlighting the need for early diagnosis.
- The study compared various echocardiographic and cardiac magnetic resonance (CMR) parameters in patients with sRV, finding significant correlations between imaging techniques and clinical outcomes, especially regarding heart function and exercise capacity.
- Results indicated that patients with cc-TGA had better global longitudinal strain values compared to those with D-TGA, suggesting differences in sRV performance between these two groups.