Publications by authors named "S Pegge"

Research Question: The goal of this study was to assess the diagnostic accuracy of spinal time-resolved contrast-enhanced MR angiography (4D-MRA) for the detection and localization of spinal dural arteriovenous fistulas (SDAVF) in our institution.

Material And Methods: Single center retrospective cohort study of patients with the clinical suspicion of a SDAVF. Patients were included who had undergone spinal 4D-MRA in the period January 2010-February 2021.

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Article Synopsis
  • * A systematic review and meta-analysis revealed that 4D-MRA has a very high sensitivity of 98.2% and a specificity of 88.2% compared to DSA for detecting SDAVFs.
  • * The findings suggest that 4D-MRA can accurately locate SDAVFs and potentially streamline the diagnostic process, reducing patient discomfort and procedural risks associated with DSA.
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Background And Purpose: Radiological features on magnetic resonance imaging (MRI) were attributed to oligodendroglioma, although the diagnostic accuracy in a real-world clinical setting remains partially elusive. This study investigated the accuracy and robustness of tumor heterogeneity and tumor border delineation on T2-weighted MRI to distinguish oligodendroglioma from astrocytoma.

Materials And Methods: Eight readers from three different specialties (radiology, neurology, neurosurgery) with varying levels of experience blindly rated 79 T2-weighted MR images of patients with either oligodendroglioma or astrocytoma.

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Background: Previous randomised controlled trials could not demonstrate that surgical evacuation of intracerebral haemorrhage (ICH) improves functional outcome. Increasing evidence suggests that minimally invasive surgery may be beneficial, in particular when performed early after symptom onset. The aim of this study was to investigate safety and technical efficacy of early minimally invasive endoscopy-guided surgery in patients with spontaneous supratentorial ICH.

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  • The study investigates the validity of subclassifying Koos 2 vestibular schwannoma (VS) tumors based on their size and proximity to the brainstem, challenging the standard practice of immediate treatment following growth detection.
  • Six experts evaluated 43 MRI scans to assess the reliability of the classification, finding a near-perfect agreement on Koos 2a tumors and high agreement on Koos 2b tumors.
  • Results showed excellent reliability among raters, suggesting that this refined classification can help inform treatment decisions that prioritize patient-centered care rather than just tumor size growth.
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