Publications by authors named "S Pearcey"
Article Synopsis
- The COVID-19 pandemic has significantly impacted parental mental health, particularly due to the challenges of balancing work and home-schooling, with increased levels of stress and depression noted among many parents during restrictions.
- A study analyzing survey data from over 5,500 parents in the UK found that stress and depression were particularly high among those with primary-school-aged children or specific working situations, while anxiety levels remained fairly stable.
- Despite the majority of parents reporting low mental health symptoms, a notable minority exhibited persistent high symptoms, largely influenced by factors such as age, single-parent status, pre-existing mental health issues, and having children with special educational needs.
Background: A major concern throughout the COVID-19 pandemic has been on young people's experiences with mental health. In this study we mapped children and adolescents' mental health trajectories over 13 months of the pandemic and examine whether family, peer, and individual-level factors were associated with trajectory membership.
Methods: This study focuses on a sub-sample from the Co-SPACE study of 3322 children and adolescents (aged 4-16 years) for whom parents completed a survey at Time 0 and at least one follow-up survey between March 2020 and May 2021.
Cardiac deficiency of P21-activated kinase 1 promotes atrial arrhythmogenesis in mice following adrenergic challenge.
Philos Trans R Soc Lond B Biol Sci
June 2023
P21-activated kinase 1 (Pak1) signalling plays a vital and overall protective role in the heart. However, the phenotypes of deficiency in the cardiac atria have not been well explored. In this study, cardiac-conditional knock-out (cKO) mice were studied under baseline and adrenergic challenge conditions.
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