Publications by authors named "S Paulin"

Article Synopsis
  • The WHO Model List of Essential Medicines (EML) focuses on prioritizing medicines that are crucial for global public health, particularly in the context of antibiotic use and resistance.
  • In response to the rise of antimicrobial resistance, the EML introduced a new classification system called AWaRe, which categorizes antibiotics into Access, Watch, and Reserve groups to guide appropriate usage.
  • The 2023 AWaRe classification includes 41 essential antibiotics and aims to enhance global antibiotic prescribing practices, promoting the use of Access antibiotics to optimize treatment and reduce misuse to prolong the effectiveness of these medications.
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There is an urgent global need for new strategies and drugs to control and treat multidrug-resistant bacterial infections. In 2017, the World Health Organization (WHO) released a list of 12 antibiotic-resistant priority pathogens and began to critically analyze the antibacterial clinical pipeline. This review analyzes "traditional" and "nontraditional" antibacterial agents and modulators in clinical development current on 30 June 2021 with activity against the WHO priority pathogens mycobacteria and Clostridioides difficile.

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