Publications by authors named "S Paul Victor"
Alzheimer's disease (AD) and Alzheimer's Related Dementias (ADRD) are projected to affect 50 million people globally in the coming decades. Clinical research suggests that Mild Cognitive Impairment (MCI), a precursor to dementia, offers a critical window of opportunity for lifestyle interventions to delay or prevent the progression of AD/ADRD. Previous research indicates that lifestyle changes, including increased physical exercise, reduced caloric intake, and mentally stimulating activities, can reduce the risk of MCI.
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- - Tree bark beetle infestations threaten forests by harming biodiversity, carbon storage, and timber resources, highlighting the need for early detection and improved forest management practices.
- - An innovative intelligent system using multispectral images and generative-adversarial networks (GANs) was developed to assess bark beetle damage, achieving a classification accuracy of 87.5% while reducing reliance on large labeled datasets.
- - The research has important implications for forestry management and ecosystem preservation, emphasizing the need for responsible implementation, integration with traditional ecological knowledge, and addressing potential risks like data misinterpretation and privacy concerns.
Background: Intravenous steroid pulses (SP) are successfully used for the treatment of patients with idiopathic nephrotic syndrome (INS) resistant to oral prednisone.
Methods: We performed a retrospective analysis of all patients in the three pediatric nephrology centers of the Paris region from 2002 to 2022 who were resistant to a 30-day course of oral prednisone and who received SP for their first INS flare and analyzed their disease course over 4 years.
Results: Forty-seven patients (17 girls), median age 3.
Cryptococcal meningoencephalitis (CM) is an opportunistic fungal infection and a major cause of death among people living with human immunodeficiency virus in sub-Saharan Africa. 5-flucytosine (5-FC) is a unique, brain-permeable antifungal agent used to reduce mortality from CM and to prevent disease in individuals carrying cryptococcal antigen. 5-FC has a short plasma half-life, requiring 6-hourly oral dosing with an immediate-release (IR) formulation, a significant challenge in hospital and outpatient settings, risking a lack of compliance.
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