Safety and immunogenicity of a serogroups A/C Neisseria meningitidis oligosaccharide-protein conjugate vaccine in young children. A randomized controlled trial.

Objective: To assess the safety and immunogenicity of a bivalent serogroups A/C meningococcal oligosaccharide-protein conjugate vaccine compared with the licensed meningococcal polysaccharide vaccine.

Design: Randomized controlled trial.

Study Population: Ninety healthy 18- to 24-month-old children who were seen at a southern California Kaiser Permanente clinic.