Publications by authors named "S Panico"

» Increased professional, personal, and emotional stress can have compounding negative effects on physicians, which can be detrimental to teamwork dynamics, workplace environment, productivity, and personal well-being. Orthopaedic surgery, in particular, is a medical specialty that demonstrates high workplace demands, elevated rates of burnout, and low workplace diversity.» Professional coaching can help combat these challenges and facilitate professional success by providing an outlet for discussion and planning toward one's career development and goals.

View Article and Find Full Text PDF

Introduction: Observational studies have shown that more educated people are at lower risk of developing type 2 diabetes (T2D). However, robust study designs are needed to investigate the likelihood that such a relationship is causal. This study used genetic instruments for education to estimate the effect of education on T2D using the Mendelian randomisation (MR) approach.

View Article and Find Full Text PDF

Background: Nutri-Score is a scientifically validated 5-color front-of-pack nutrition label reflecting the nutrient profile of foods. It has been implemented in several European countries on a voluntary basis, pending the revision of the European labeling regulation. Hence, scientific evidence is needed regarding the ability of the nutrient profile underlying the Nutri-Score (uNS-NPS, 2023-updated version) to characterize healthier foods.

View Article and Find Full Text PDF

Background: Alterations in gut microbiota are observed in Parkinson's disease (PD). Previous studies on microbiota-derived metabolites in PD were small-scale and post-diagnosis, raising concerns about reverse causality.

Objectives: Our goal was to prospectively investigate the association between plasma microbial metabolites and PD risk within a metabolomics framework.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates which polygenic scores (PGSs) for coronary artery disease (CAD) are most effective in identifying high-risk individuals within the Italian population, highlighting the need for tailored genetic risk assessment tools.
  • Using data from two independent Italian cohorts, the researchers analyzed 266 PGSs and found that 49 of them showed significantly different distributions between CAD patients and controls, with PGS003727 being the most accurate.
  • The findings suggest that existing European CAD PGSs may not be uniformly applicable across different populations, emphasizing the importance of further validation for clinical use in specific regions like Italy.
View Article and Find Full Text PDF