Decoding the Catalytic Potential of Dinuclear 1-Row Transition Metal Complexes for Proton Reduction and Water Oxidation.

The growing interest in renewable energy sources has led to a significant focus on artificial photosynthesis as a means of converting solar energy into lucrative and energy-dense carbonaceous fuels. First-row transition metals have thus been brought to light in the search for efficient and high-performance homogenous molecule catalysts that can accelerate energy transformation and reduce overpotentials during the catalytic process. Their dinuclear complexes have opportunities to enhance the efficiency and stability of these molecular catalysts, primarily for the hydrogen evolution reaction (HER) and water oxidation reaction (WOR).

TTFA-Platin Conjugate: Deciphering the Therapeutic Roles of Combo-Prodrug through Evaluating Stability-Activity Relationship.

This work introduces a novel Pt(II) based prodrug TTFA-Platin that integrates a β-diketonate ligand TTFA with a platinum scaffold to structurally resemble carboplatin and offers intermediate kinetic lability between cisplatin and carboplatin, striking a balance between therapeutic efficacy and safety. A comprehensive stability and speciation study was conducted in various biological media, mapping the therapeutic effects of TTFA-Platin. A control molecule, TMK-Platin, was synthesized to further validate the structural-stability relationship, which displayed poor activatable features in biological systems.

Cross-frontal variability of phytoplankton productivity in the Indian sector of the Southern Ocean during austral summer of 2010-2018.

Oceanic phytoplankton productivity, which regulates atmospheric CO, is crucial for unraveling the complexities of the global carbon cycle. Despite its substantial contribution to the global carbon budget and its critical role in anthropogenic carbon sink, the Southern Ocean (SO) remains under-sampled due to logistical challenges. The present study attempts to elucidate the variability of water column primary production (PP) in the Indian Sector of the Southern Ocean (ISSO) by examining associated physicochemical parameters and physiological conditions of phytoplankton that drive this variability.

Development and Validation of Near-Infrared Reflectance Spectroscopy Prediction Modeling for the Rapid Estimation of Biochemical Traits in Potato.

Potato is a globally significant crop, crucial for food security and nutrition. Assessing vital nutritional traits is pivotal for enhancing nutritional value. However, traditional wet lab methods for the screening of large germplasms are time- and resource-intensive.

Production and characterization of anti-hypertensive and anti-diabetic peptides from fermented sheep milk with anti-inflammatory activity: in vitro and molecular docking studies.

Background: The present study aimed to evaluate the anti-hypertensive and anti-diabetic activities from biologically active peptides produced by fermented sheep milk with Lacticaseibacillus paracasei M11 (MG027695), as well as to purify and characterize the angiotensin-converting enzyme (ACE) inhibitory and anti-diabetic peptides produced from fermented sheep milk.

Results: After 48 h of fermentation at 37 °C, sheep milk demonstrated significant changes in anti-diabetic effects and ACE-I effects, with inhibition percentages observed for ACE inhibition (76.32%), α-amylase (70.