Publications by authors named "S Pacheco"
Respiratory syncytial virus (RSV) is an important cause of severe respiratory disease in older adults. Understanding the disease burden is crucial for guiding vaccination policy and raising disease awareness. We estimated the burden of RSV hospitalizations and deaths in adults in five middle-income countries: Argentina, Brazil, Chile, Mexico, and Malaysia.
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- * New techniques like whole-transcriptome and single-cell sequencing identified a specific immune cell population, MG-Act, in certain pediatric gliomas, which express the TIM3 protein linked to inflammation and immune response.
- * Treating a mouse model of low-grade gliomas with anti-TIM3 significantly increased survival compared to standard treatments, suggesting that anti-TIM3 could be a promising option for clinical trials targeting pediatric MAPK-driven gliomas.
Prevalence and Classification of C-Shaped Canal and Radix in Mandibular Molars Using Cone-Beam Computed Tomography on Mexican Population.
Dent J (Basel)
July 2024
Article Synopsis
- The study examines the complexity of teeth anatomy, especially focusing on C-shaped canals and radix entomolaris, which impact the effectiveness of root canal treatments.
- Using cone-beam computed tomography (CBCT), researchers identified the prevalence and types of these anatomical variations in a sample of 2173 teeth from a Mexican population.
- Results showed that C-shaped canals were more common in second mandibular molars, with a significant gender difference in prevalence, highlighting the importance of understanding these variations for improving endodontic treatment success rates.
STING agonists can reprogram the tumor microenvironment to induce immunological clearance within the central nervous system. Using multiplexed sequential immunofluorescence (SeqIF) and the Ivy Glioblastoma Atlas, STING expression was found in myeloid populations and in the perivascular space. The STING agonist 8803 increased median survival in multiple preclinical models of glioblastoma, including QPP8, an immune checkpoint blockade-resistant model, where 100% of mice were cured.
View Article and Find Full Text PDFCorrection: Prevalence and factors associated with self-reported anxiety in adults during the COVID-19 pandemic in Argentina, Brazil, Peru, Mexico, and Spain: A cross-sectional Ibero-American study.
PLoS One
June 2024
[This corrects the article DOI: 10.1371/journal.pone.
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