First Determination of the Spin-Parity of Ξ_{c}(3055)^{+,0} Baryons.

The Ξ_{b}^{0(-)}→Ξ_{c}(3055)^{+(0)}(→D^{+(0)}Λ)π^{-} decay chains are observed, and the spin-parity of Ξ_{c}(3055)^{+(0)} baryons is determined for the first time. The measurement is performed using proton-proton collision data at a center-of-mass energy of sqrt[s]=13  TeV, corresponding to an integrated luminosity of 5.4  fb^{-1}, recorded by the LHCb experiment between 2016 and 2018.

Semi-synthesis of functionalized cell-permeable ubiquitin probes SrtA-mediated ligation.

Cell-permeable ubiquitin (Ub) probes labeled with a fluorescent or biotin tag have become effective tools for studying the activity of deubiquitinating enzymes (DUBs) in living cells. However, such probes are usually obtained through total chemical synthesis. In this study, we develop a Sortase A (SrtA)-mediated semi-synthetic strategy for preparing cell-permeable Ub-propargylamide (Ub-PA) with a fluorescent or biotin tag.

Function of levator palpebrae superioris in dry eye disease.

Purpose: To evaluate the effect of levator palpebrae superioris in patients with dry eye disease.

Methods: 168 eyes of 84 patients (group 1 = fair levator function ≤ 9 mm, 78 eyes; group 2 = good levator function > 9 mm, 90 eyes) were retrospectively enrolled. Levator function test, Ocular Surface Disease Index Questionnaire (OSDI), Schirmer I test, noninvasive tear break up time (NItBUT), corneal staining score, meibography, meibum quality and expressibility scores, tear meniscus height, and partial blinking rate (PBR) were examined.

Research progress on the anti-aging effect of polysaccharides of traditional Chinese medicine: Using Caenorhabditis elegans as an animal model.

With the growing elderly population and increasing incidence of various aging-related diseases, the scientific community is faced with an urgent challenge to identify natural anti-aging agents. Traditional Chinese medicine (TCM) polysaccharides have been proven to have good anti-aging activities. This article reviews the literature on the anti-aging pathways of traditional Chinese medicine polysaccharides applied to Caenorhabditis elegans models in the past decade.

Analysis of New Psychoactive Substances： Nitazenes.

Nitazenes are a class of synthetic opioids that have recently emerged in the illegal drug market. They are characterized by high potency and a narrow therapeutic window. Compared with traditional opioids, these substances are more likely to cause severe respiratory depression.