Publications by authors named "S P Xavier"
Neurodevelopmental disorders pose significant clinical challenges related to atypical brain development, often manifesting as learning disabilities, developmental delays, intellectual deficits, behavioral issues, epilepsy, and sleep disturbances. Among genetic neuropsychiatric conditions, synaptopathies are notable for their impact on synaptic function, resulting in varied neuropsychiatric phenotypes. Among these, SYNGAP1-associated syndrome is characterized by intellectual disability, global developmental delay, autism, and epilepsy, primarily due to loss-of-function mutations.
View Article and Find Full Text PDFBackground: A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet. The aim was to evaluate the influence of this novel association on the processes of bone regeneration in maxillary sinus augmentation.
Methods: In this prospective, randomized, within-animal model, maxillary sinus augmentation was performed bilaterally in 12 rabbits.
Background And Aim: We aimed to develop and validate a simple capsule endoscopy (CE) training assessment tool, the Capsule Endoscopy Training Assessment (CETA), and prospectively use it to analyze the learning progression achieved by participants in our CE training program.
Methods: Over a 3-year period, all participants in our CE training program completed pre-training and post-training CETA, ranging between 0% and 100%, and encompassing theoretical questions and interpretation of segmented CE videos. We compared the mean differences in overall, theoretical, and practical pre-training and post-training CETA, and assessed the influence of previous endoscopic experience (upper gastrointestinal endoscopy [UGE], colonoscopy, device-assisted enteroscopy [DAE] and CE) using generalized linear models.
Article Synopsis
- - The study aimed to review and meta-analyze RNA sequencing research comparing brain tissue from Alzheimer's disease patients to control subjects, focusing on study quality and identifying important genes and pathways linked to the disease.
- - Researchers examined 3,266 published studies and included 24 that met their criteria, discovering 571 differentially expressed genes in the temporal lobe and 189 in the frontal lobe, highlighting pathways like "Tube morphogenesis" and "Neuroactive ligand-receptor interaction."
- - The review faced challenges due to study differences and limited data but emphasizes that thorough methods are crucial for understanding Alzheimer's transcriptomic changes, which can help in the development of biomarkers and treatments.
Unusual partners: a rare cause of small bowel bulges and a common cause of anemia.
Rev Esp Enferm Dig
October 2024
Article Synopsis
- * Imaging showed intestinal pneumatosis in her proximal jejunum and right colon, and upper endoscopy diagnosed non-atrophic gastritis with an H.pylori infection, which was treated.
- * A small bowel capsule endoscopy and enteroscopy revealed bulging areas in the bowel, which were treated successfully using coagulation and clips, resulting in the patient being asymptomatic and free from anemia after six months.