Publications by authors named "S P Rajagopal"
Background: High spinal anesthesia (HSA) has been utilized in cardiac surgery; however, there is limited evidence on its impact on facilitating postoperative recovery. This study aimed to evaluate the impact of HSA in pediatric congenital heart surgery on postoperative recovery.
Methods: A single center, propensity score-matched retrospective cohort study was designed using data from pediatric patients under 18 years old, who underwent congenital heart surgeries classified as Risk Adjustment for Congenital Heart Surgery-1 (RACHS-1) score 3 or less.
Article Synopsis
- * Specific ncRNAs regulate crucial signaling pathways (e.g., Wnt, Notch, Hedgehog) that affect CSC traits like self-renewal and differentiation, with some microRNAs inhibiting these processes while certain lncRNAs enhance stemness.
- * Understanding the interplay between ncRNAs and CSCs can lead to innovative targeted therapies that address aggressive and treatment-resistant cancers, providing new avenues for effective cancer treatment.
Article Synopsis
- Half of female kidney transplant recipients are of reproductive age, but there's a lack of data on their reproductive practices and counseling.
- A survey found that 26% of female kidney transplant patients were unaware of their ability to get pregnant post-transplant, and while 72% used contraception, many relied on less reliable methods.
- Most patients felt pre-transplant counseling was inadequate, though many were satisfied with post-transplant advice, highlighting a need for better education on pregnancy and contraception to lower health risks.
Pilot Randomized Clinical Trial of a Passive Non-invasive Positive End-Expiratory Pressure (PEEP) Device for Delivering Positive Pressure Therapy Compared to Standard Care in Non-critically Ill Patients With COVID-19.
Cureus
October 2024
Background: During the COVID-19 pandemic, there were reports of a shortage of ventilators and oxygen supply, particularly in resource-limited settings. We report the preliminary evaluation of a non-invasive positive end-expiratory pressure (PEEP) mask in hospitalized non-critically ill patients with COVID-19.
Methods: We randomly assigned hospitalized adult patients with confirmed COVID-19 infection and requiring greater than 40% supplemental oxygen to either standard care oxygen delivery (control) or via Materialise passive non-invasive PEEP device mask (intervention; Belgium).