Publications by authors named "S P Lupisan"

Article Synopsis
  • The study focused on the prevalence of antibodies against four endemic human coronaviruses (HCoV-229E, HCoV-NL63, HCoV-HKU1, and HCoV-OC43) among children in the Philippines and their potential reaction to SARS-CoV-2.
  • Researchers analyzed 315 serum samples from children collected between 2015 and 2018, finding high seroprevalence rates: HCoV-229E (63.8%), HCoV-NL63 (71.4%), HCoV-HKU1 (76.5%), and HCoV-OC43 (83.5%).
  • Despite 21.9% of samples showing reactivity
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Introduction: The high burden of respiratory syncytial virus (RSV) infection in young children disproportionately occurs in low- and middle-income countries (LMICs). The PROUD (Preventing RespiratOry syncytial virUs in unDerdeveloped countries) Taskforce of 24 RSV worldwide experts assessed key needs for RSV prevention in LMICs, including vaccine and newer preventive measures.

Methods: A global, survey-based study was undertaken in 2021.

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Article Synopsis
  • Rhinoviruses (RVs) are common causes of severe respiratory infections in hospitalized children, categorized into three species: RV-A, RV-B, and RV-C, with RV-C further divided into several clades.
  • A study in rural Philippines examined clinical data from children under 5 years old, revealing 713 cases of RV infections among 3680 respiratory illness episodes, predominantly RV-C.
  • The findings indicated that children with RV-C, especially the GAC1 clade, experienced more severe respiratory symptoms compared to those infected with RV-A or RV-B, highlighting RV-C's role in severe illnesses.
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Objective: Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory infection, and therefore, a major threat to global health. This study determined the epidemiological and molecular characteristics of RSV among cases of influenza-like illness (ILI) and severe acute respiratory infection (SARI) among children in the Philippines.

Method: The study included archived nasopharyngeal swab and oropharyngeal swab samples collected from patients under the age of five who are presented with ILI or SARI for the period of 2006-2016.

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