Publications by authors named "S P Lezhava"
We studied viability of adenosine-modified monocytes after cryopreservation and their regenerative potential. The optimal method of cell cryopreservation was the use of serum-free medium followed by storage in liquid nitrogen. Injections of adenosine-modified monocytes after 12-week cryopreservation around grade IIIB burn wound accelerated healing of the skin defect and significantly improved the histological pattern of the damage area at delayed terms.
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- * It was found that the best modification conditions involved a reaction at 40 °C with an equimolar amount of PMIDA for 3.5 hours, resulting in good colloidal stability and high magnetic properties of the MNPs.
- * The PMIDA-modified MNPs showed superior performance with relaxivity values of 341 and 102 mmol s, and were successfully tested as a T1 contrast agent for liver imaging in vivo, indicating their potential medical application.