Publications by authors named "S P Khanuja"

Article Synopsis
  • The study aimed to compare the effectiveness of intravenous dexmedetomidine versus a combination of low-dose ketamine and dexmedetomidine for extending spinal anesthesia in lower limb orthopedic surgeries.
  • Conducted on 60 patients, the study divided them into two groups: one receiving only dexmedetomidine (Group D) and the other receiving a mix of ketamine and dexmedetomidine (Group LKD).
  • Results showed similar anesthesia duration between groups, but Group D experienced more hypotension episodes, while Group LKD required less tramadol post-surgery.
View Article and Find Full Text PDF

Background: N95 filtering facepiece respirators (FFR) are used by health care workers for prevention of airborne infection, and its use has increased manifolds during COVID-19 pandemic. Prolonged use may result in carbon dioxide (CO) accumulation, affect hemodynamics, and blood gas values. Although arterial blood gas values accurately measure the blood CO levels, venous blood gas values also show acceptable correlation.

View Article and Find Full Text PDF

Filling defects identified in the pulmonary arterial tree are commonly presumed to represent an embolic phenomenon originating from thrombi formed in remote veins, particularly lower-extremity deep venous thrombosis (DVT). However, accumulating evidence supports an underappreciated cause for pulmonary arterial thrombosis (PAT), namely, de novo thrombogenesis-whereby thrombosis arises within the pulmonary arteries in the absence of DVT. Although historically underrecognized, in situ PAT has become of heightened importance with the emergence of SARS-CoV-2 infection.

View Article and Find Full Text PDF

Background And Aims: A definitive cutoff of inferior venacava (IVC) diameter in expiration (dIVCmax) and inferior vena cava collapsibility index (IVCCI) for predicting general anaesthesia associated hypotension (GAAH) is not yet determined. Primary objective of this study was to determine the correlation of dIVCmax and IVCCI, with GAAH. Other objectives were to determine the correlation of these IVC parameters with preoperative fasting duration, temperature and humidity.

View Article and Find Full Text PDF

Papaver somniferum produces therapeutically useful benzylisoquinoline alkaloids (BIAs) like papaverine, thebaine, codeine, and morphine that accumulate in its capsular latex. Morphine is a potent analgesic but is also abused as a narcotic, which has increased the demand for non-narcotic thebaine that can be converted into various analgesics. To curtail the narcotic menace, many distinct genotypes of the plant have been developed that are deficient in morphine and/or latex.

View Article and Find Full Text PDF