Carbon monoxide exposure inside UK road vehicles: a pilot study.

Environmental CO presents a risk to public health. The effects of chronic low-level CO exposure are well-documented, with pregnant women, the unborn and children being particularly vulnerable. Although a number of studies have investigated the phenomenon, its current prevalence in the UK has not been examined.

Lipoteichoic acid biosynthesis by is controlled by the MspA protein.

produces a plethora of virulence factors critical to its ability to establish an infection and cause disease. We have previously characterized a small membrane protein, MspA, which has pleiotropic effects on virulence and contributes to pathogenicity . Here we report that inactivation triggers overaccumulation of the essential cell wall component, lipoteichoic acid (LTA), which, in turn, decreases autolytic activity and leads to increased cell size due to a delay in cell separation.

Identifying competencies for an advanced practice physiotherapy role within an interprofessional chronic pain clinic.

Background: Advanced practice physiotherapy (APP) models of care have shown success in access, safety, satisfaction, and care quality for musculoskeletal pain conditions in various settings. Yet, there is a gap in defining competencies for physiotherapists to be the initial point of contact for people with chronic pain. This study aims to identify and agree upon the competencies necessary for a physiotherapist to fulfill the role of an APP in an interprofessional chronic pain clinic.