Quantum-chemical simulation of the adsorption-induced reduction of strength of siloxane bonds.

Mechanical strength of silicate glasses is known to decrease markedly due to the adsorption of molecules from the environment, especially in aqueous alkali solutions. This effect, known as the adsorption-induced reduction of strength (AIRS), has not yet been fully understood. Here, the dependence on the chemical nature and electronic properties of adsorbates of the AIRS of siloxane bonds in silica was studied by means of quantum-chemical calculations at the wB97X-D3/def2-TZVP level of theory.

Meningitis after percutaneous radiofrequency trigeminal ganglion lesion. Case report and review of literature.

Case Report: A 79-year-old man with severe trigeminal neuralgia presented to the pain clinic, and was offered a radiofrequency trigeminal ganglion lesion. He had only partial response to the first procedure, so a second was undertaken. The following day he presented with signs of meningitis and the diagnosis was confirmed on lumbar puncture.

Temperature and pressure dependences of tunneling rate constant: density-functional theory potential-energy surface for H-atom transfer in the fluorene-acridine system.

Temperature and pressure dependences of rate constants for solid phase tunneling reactions are analytically considered within the framework of modified theory of radiationless transitions, taking into account the intermolecular and soft intramolecular promotive vibrations of reagents. This treatment allows us to describe theoretically the process of atomic tunneling and the effect of temperature on the potential barrier and reorganization of the reagents. The influence of external pressure appears in our treatment as a static reduction of widths and heights of the potential barrier with hydrostatic compression of the matrix, and also as an increase of frequencies of promotive vibrational modes owing to anharmonicity.

Tolerability of acute postoperative pain management: nausea, vomiting, sedation, pruritus, and urinary retention. Evidence from published data.

This review examines the evidence from published data concerning the tolerability (indicated by the incidence of nausea, vomiting, sedation, pruritus, and urinary retention), of three analgesic techniques after major surgery; intramuscular analgesia (i.m.), patient-controlled analgesia (PCA), and epidural analgesia.

Pre-operative and post-operative effect of a pain management programme prior to total hip replacement: a randomized controlled trial.

Patients may wait some time for total hip replacement with conservative management of pain and disability, but no attempts to rehabilitate them. This study randomised 40 patients accepted for and awaiting total hip replacement to a brief rehabilitative psychologically based pain management programme (PMP) or to a control group with no intervention. Patients were assessed before randomisation, 3 months after the PMP or equivalent waiting time, and again one year later after total hip replacement.