Proximal Tibial Fracture in Pseudo-Rheumatoid Synovial Chondromatosis: A Case Study.

Introduction: Progressive pseudorheumatoid dysplasia is an autosomal recessively inherited rare disorder with features of growth retardation, multiple joint deformities, and intra-articular loose bodies.

Case Report: This case study is about a 34-year-old man who presented to us following trauma to his right leg. On general assessment, he was short statured with multiple deformities of both upper and lower limbs with local signs suggestive of proximal tibial fracture over his right tibia.

Loss of immune cell identity with age inferred from large atlases of single cell transcriptomes.

By analyzing two large atlases of almost 4 million cells, we show that immune-senescence involves a gradual loss of cellular identity, reflecting increased cellular heterogeneity, for effector, and cytotoxic immune cells. The effects are largely similar in both males and females and were robustly reproduced in two atlases, one assembled from 35 diverse studies including 678 adults, the other the OneK1K study of 982 adults. Since the mean transcriptional differences among cell-types remain constant across age deciles, there is little evidence for the alternative mechanism of convergence of cell-type identity.

MCPNet: a parallel maximum capacity-based genome-scale gene network construction framework.

Motivation: Gene network reconstruction from gene expression profiles is a compute- and data-intensive problem. Numerous methods based on diverse approaches including mutual information, random forests, Bayesian networks, correlation measures, as well as their transforms and filters such as data processing inequality, have been proposed. However, an effective gene network reconstruction method that performs well in all three aspects of computational efficiency, data size scalability, and output quality remains elusive.

Knowledge, attitude, and awareness of biocompatibility of orthodontic materials among dental students.

The aim of this study is to find the knowledge, attitude and awareness of biocompatibility of orthodontic materials among dental students.A survey of 13 questions was created using Google Forms. The questions on the survey cover a wide range of topics including the awareness of cytotoxicity of orthodontic materials, their corrosive potential, ways of preventing corrosion and release of subsequent substances, and various means by which these physiological actions occur.

Interfacial cavitation.

Cavitation has long been recognized as a crucial predictor, or precursor, to the ultimate failure of various materials, ranging from ductile metals to soft and biological materials. Traditionally, cavitation in solids is defined as an unstable expansion of a void or a defect within a material. The critical applied load needed to trigger this instability -- the critical pressure -- is a lengthscale independent material property and has been predicted by numerous theoretical studies for a breadth of constitutive models.