Catheter-Based Renal Denervation for Resistant Arterial Hypertension: 10-Year Real-World Follow-Up Data.

This analysis of real-world data examines the efficacy, safety, and long-term outcomes of renal denervation in hypertensive patients for up to 10 years. Sixty-five consecutive patients underwent renal denervation (RDN) (single operator) for uncontrolled resistant hypertension. Efficacy was defined as the interindividual change of office (OBPM) and ambulatory blood pressure monitoring (ABPM) at 1, 6, 12 months, 2-4 and 5-10 years after RDN.

Attitudes towards geroprotection: measuring willingness, from lifestyle changes to drug use.

Introduction: Geroprotection is an emerging field of research focused on devising strategies for combating the mechanisms of ageing. This study held three aims: 1) to explore the willingness to utilise five different geroprotective measures (i.e.

Cubicle design and dairy cow rising and lying down behaviours in free-stalls with insufficient lunge space.

Cubicle partitions divide the resting area of free-stalls into individual lying places for cows, thereby facilitating the maintenance of good hygiene and reducing competition by separating animals. The forward lunge space in lying cubicles is often insufficient for a natural head lunge movement during rising. Cubicles with open frame partitions and a flexible neck strap aim to alleviate this welfare issue.

Vascular Remodeling in Coronary Microvascular Dysfunction.

Background: Approximately one-half of the patients with angina and nonobstructive coronary artery disease (ANOCA) have evidence of coronary microvascular dysfunction (CMD).

Objectives: This study aims to characterize patients with ANOCA by measuring their minimal microvascular resistance and to examine the pattern of vascular remodeling associated with these measurements.

Methods: The authors prospectively included patients with ANOCA undergoing continuous thermodilution assessment.