A case series describing the multidisciplinary management of pulmonary arterial hypertension in pregnancy: Time for optimism.

Background: Pulmonary arterial hypertension (PAH) is a high-risk condition during pregnancy, with recent literature describing mortality rates of up to 23%.

Aim: To describe the course and outcomes of pregnancy for women with PAH in a major Australian metropolitan referral centre over a 15-year period.

Methods: Retrospective review of medical records of all pregnant women with PAH over the period 2005-2020.

Hourly human chorionic gonadotropin secretion profiles during the peri-implantation period of successful pregnancies.

Objective: To characterize the hourly profiles of hCG secretion in blood during conceptive cycles that ended in successful pregnancy.

Design: Prospective study.

Setting: University fertility clinic and research laboratories.

Secretion and excretion of human chorionic gonadotropin during early pregnancy.

Objective: To characterize the profiles of human chorionic gonadotropin (hCG) secretion in blood and its subsequent excretion in urine during conceptive cycles that ended in successful pregnancy and in spontaneous abortion.

Design: A prospective study.

Setting: University fertility clinic and research laboratories.

Clinical evaluation of luteal function.

Objective: To determine the ability of luteal phase length determined by basal body temperature (BBT) pattern and a midluteal serum progesterone level to predict the result of an endometrial biopsy in a subsequent cycle.

Methods: We performed a retrospective analysis of 141 women with a history of infertility who were being evaluated for luteal function. The luteal phase length determined from a BBT chart of one menstrual cycle was compared to a single midluteal serum progesterone level from a second menstrual cycle.