Publications by authors named "S Ottaviani"
Introduction: Age-related changes occurring in the kidney can lead to a reduction in Glomerular Filtration Rate (GFR); especially in older adults with multimorbidity and/or frailty, an accurate evaluation of kidney function is critical. For the estimation of GFR in patients over 70 years, CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) is often used. However, validated equations exist for old-age populations like BIS1 (Berlin Initiative Study 1) and FAS (Full Age Spectrum).
View Article and Find Full Text PDFBackground/objectives: Over 60% of diagnoses of head and neck squamous cell carcinoma (HNSCC) occur in patients aged over 65. The benefits of radiotherapy (RT) combined with chemotherapy remain controversial in geriatric patients. Frailty stratification is underutilized in clinical practice despite evidence suggesting its predictive power.
View Article and Find Full Text PDFObjective: To develop and validate a patient-reported definition of acute calcium pyrophosphate (CPP) crystal arthritis in people with crystal-proven CPP deposition (CPPD) disease.
Methods: Consecutive patients with crystal-proven CPPD disease from seven centres across four countries were enrolled in a cross-sectional study. In each centre, patient-reported outcomes on the features of acute CPP crystal arthritis were collected.
Article Synopsis
- Alpha-1 Antitrypsin Deficiency (AATD) is linked to higher risks of lung and liver diseases, primarily associated with the common PI*ZZ genotype.
- Researchers studied patients with severe AATD from the Italian Registry for AATD, focusing on those with rare genotypes like PI*R.
- Results showed that patients with rare genotypes exhibited similar clinical characteristics and respiratory profiles to those with the PI*ZZ genotype, emphasizing the need for timely diagnosis of PI*R for effective management.