Publications by authors named "S Ordies"
Article Synopsis
- - The study focuses on chronic rejection in lung transplantation, exploring its nature, timing, and location, challenging the idea that it primarily affects airways.
- - Researchers conducted experiments on mice, sacrificing them at different time points post-transplantation to analyze the progression of chronic rejection through histology and advanced imaging techniques.
- - Findings revealed that chronic rejection begins with innate inflammation around small arteries and evolves through various stages, ultimately affecting bronchioles, suggesting that the process may not align with current beliefs about Chronic Lung Allograft Dysfunction (CLAD).
Background: Anesthesia during thrombectomy remains a matter of debate. We retrospectively investigated the influence of intraprocedural blood pressure and type of anaesthetic agent on 3-month functional outcome and mortality in stroke patients undergoing mechanical thrombectomy under general anesthesia in a single center study.
Methods: All patients suffering from stroke who presented between January 2019 and July 2021 at Ziekenhuis Oost-Limburg Genk, Belgium and who received thrombectomy were included.
Article Synopsis
- - The assessment of donor lungs for transplantation is mostly subjective and varies greatly, lacking standardized criteria; researchers explored using a CT-based machine learning algorithm to evaluate donor lungs before surgery.
- - The study collected clinical data and CT scans from 100 cases, training a machine learning method called dictionary learning to identify specific image patterns related to lung health.
- - The algorithm successfully detected lung abnormalities, highlighting patients with a higher risk of complications post-transplant and emphasizing the need for objective screening methods as the use of less-than-ideal donor lungs increases.
Article Synopsis
- - The study investigates the relationship between right ventricular function and lung injury during lung transplantation, focusing on how ischemia-reperfusion injury affects the transplanted lung itself, using a porcine model for research.
- - Researchers observed that forcing blood through a lung affected by ischemia-reperfusion injury significantly increased resistance and led to right ventricular failure in some animals, highlighting distinct responses in failing versus non-failing ventricles.
- - The findings suggest a complex interplay between lung injury and right ventricular function, emphasizing the potential benefits of using extracorporeal life support during lung transplantation procedures to mitigate these effects.