[Utility of Point Dose Verification Using Measured Ionization Amount Ratio of Reference Irradiation to Volumetric Modulated Arc Therapy].

In the point dose verification of intensity-modulated radiation therapy (IMRT), we compared the commonly used method of measuring absolute dose (absolute method) with the measurement method by the American Association of Physicists in Medicine Task Group 119, which describes the point dose verification for IMRT using the ratio of reference irradiation and measured ionization. The target was 66 plans for head and neck cancer, 46 plans for lung cancer with 6 MV X-ray, and 31 plans for prostate cancer with 10 MV X-ray. They were treated with volumetric-modulated arc therapy (VMAT).

Impact of different Ir-192 source models on dose calculations in high-dose-rate brachytherapy.

In high-dose-rate brachytherapy, the geometry of the radioactive source is sometimes updated. Some institutions use a different source model for the dose calculation in treatment planning and treatment. The effects of this discrepancy were examined for four types of treatment plans, and ten patients were selected for each treatment plan.

Non-toxic Level of Acetaminophen Potentiates Carbon Tetrachloride-Induced Hepatotoxicity in Mice.

A wide range of medications are routinely used to maintain and improve human health. Hence, it is essential that we understand and predict adverse effects caused by the combined use of multiple medications. In the present study, we investigated whether the combination of carbon tetrachloride (CCl) and acetaminophen (APAP) had a detrimental effect on the liver.

Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice.

The aim of this study was to determine whether calcium potentiates acute carbon tetrachloride (CCl4) -induced toxicity. Elevated calcium levels were induced in mice by pre-treatment with cholecalciferol (vitamin D3; V.D3), a compound that has previously been shown to induce hypercalcemia in human and animal models.

Kampo formula "Hochu-ekki-to" suppressed carbon tetrachloride-induced hepatotoxicity in mice.

Objective: The aim of this study was to investigate whether pretreatment with the Japanese herbal medicine "Hochu-ekki-to" (TJ-41) has an ameliorative effect on carbon tetrachloride (CCl)-induced hepatotoxicity through anorexia prevention.

Methods: Twenty-four hours before CCl injection, TJ-41 or saline solution was intraperitoneally administered. Furthermore, 24 h after TJ-41 injection, mice were intraperitoneally administered 1.