Publications by authors named "S Omote"

Article Synopsis
  • The study aims to create a decision tree model to identify heart failure patients needing therapeutic drug monitoring (TDM) for high levels of mono-desethylamiodarone (MDEA), an amiodarone metabolite linked to tissue toxicity.
  • A retrospective cohort of 157 adults was analyzed to determine MDEA plasma concentrations, using a statistical algorithm that identified key risk factors affecting these levels.
  • Results showed that patients on more than 100 mg of amiodarone daily and with a body mass index of 22.3 kg/m² or less are at significant risk for elevated MDEA levels, suggesting the need for regular monitoring to prevent potential toxicity.
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Heart failure (HF) can cause metabolic imbalances, leading to anabolic resistance and increased energy expenditure, which often results in weight loss and cachexia. Comprehensive cardiac rehabilitation (CR), including exercise, nutritional support, and risk management, is crucial for enhancing the health and quality of life of patients with HF and is expected to play a central role in the prevention and treatment of HF-associated cachexia. However, the prevalence of cachexia in patients with HF undergoing comprehensive outpatient CR is currently unknown, and the detailed characteristics including of motor function of such patients remain undefined.

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Background: Japan has experienced a rapid decline in birth rate and an aging population, coupled with women choosing to delay having children. Family carers are therefore increasingly expected to accept simultaneous responsibilities for both children and parents. This responsibility often falls on women in Japan, but little is known about their views.

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Objectives This study was aimed at clarifying characteristics of ethical dilemmas and behaviors in the support process of older adults and their families among nurses at community general support centers.Methods A self-administered questionnaire survey was mailed to 449 nurses at community general support centers in Tokyo. Question items enquired their age, employment license, years of experience as a nurse, the presence of ethics-related organizations, number of cases in which nurses faced difficulties in supporting older adults and their families in decision making over the past year, the ethical dilemmas they experienced and their situations, and ethical behavior in the process of supporting older adults and their families.

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Young-onset dementia (YOD) occurs at <65 years of age. Individuals with YOD experience social and psychological disturbances, including a loss of employment. This economic toll affects them, their families, and their caregivers.

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