Publications by authors named "S Ohlmeier"
Article Synopsis
- - Vildagliptin, a medication for type 2 diabetes, significantly increases the risk of developing bullous pemphigoid, an autoimmune skin disease, but the mechanism behind this is unclear.
- - Researchers studied the skin proteins of nondiabetic mice treated with vildagliptin for 12 weeks, finding numerous changes in protein expression linked to cytoskeleton remodeling, despite no visible skin symptoms.
- - The study suggests that while there are no immediate clinical effects, alterations in skin protein levels could contribute to immune system problems, potentially leading to bullous pemphigoid under certain conditions.
Article Synopsis
- Preterm birth, occurring before 37 weeks of pregnancy, is a significant global health issue with unclear molecular causes and no reliable biomarkers for prediction.* -
- The study focused on analyzing placental proteins related to spontaneous preterm birth, identifying damaging gene variants, and studying specific protein functions and locations within the placenta.* -
- The findings highlight that reduced levels of the protein alpha-1 antitrypsin (SERPINA1) may increase vulnerability to inflammation and protease activity, potentially leading to spontaneous preterm birth.*
Having a Break or Being Imprisoned: Influence of Subjective Interpretations of Quarantine and Isolation on Boredom.
Int J Environ Res Public Health
February 2022
Boredom has been identified as one of the greatest psychological challenges when staying at home during quarantine and isolation. However, this does not mean that the situation necessarily causes boredom. On the basis of 13 explorative interviews with bored and non-bored persons who have been under quarantine or in isolation, we explain why boredom is related to a subjective interpretation process rather than being a direct consequence of the objective situation.
View Article and Find Full Text PDFBackground: FINCA disease is a pediatric cerebropulmonary disease caused by variants in the NHL repeat-containing 2 (NHLRC2) gene. Neurological symptoms are among the first manifestations of FINCA disease, but the consequences of NHLRC2 deficiency in the central nervous system are currently unexplored.
Methods: The orthologous mouse gene is essential for development, and its complete loss leads to early embryonic lethality.
Introduction: The vitamin D binding protein (VDBP, also known as GC-globulin) and vitamin D deficiency have been associated with chronic obstructive pulmonary disease (COPD). rs7041 and rs4588 are two single nucleotide polymorphisms of the VDBP gene, including three common allelic variants (GC1S, GC1F and GC2). Previous studies primarily assessed the serum levels of vitamin D and VDBP in COPD.
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