Publications by authors named "S Oberfield"
Article Synopsis
- The study investigates the global prevalence of polycystic ovary syndrome (PCOS) in adolescents, using two different diagnostic criteria: the old Rotterdam criteria and the updated International Evidence-based PCOS Guideline.
- Out of 15,708 articles reviewed, 24 studies covering different world regions were included in the meta-analysis, which found PCOS prevalence to be 9.8% under the Rotterdam criteria and 6.3% under the new guidelines.
- The findings suggest that the new guidelines may help prevent over-diagnosis by excluding certain criteria related to normal puberty, while still emphasizing the importance of monitoring adolescents with irregular cycles or signs of hyperandrogenism.
Background: Obesity disproportionately affects marginalized and low-income populations. Birth parent obesity from the prenatal period and childhood has been associated with child obesity. It is unknown whether prenatal or postnatal birth parent obesity has differential effects on subsequent changes in adiposity and metabolic health in children.
View Article and Find Full Text PDFObjective: The objective of this study was to examine associations between umbilical cord mitochondrial DNA copy number (mtDNAcn) and adiposity across childhood.
Methods: In a prospective birth cohort of Dominican and African American children from New York City, New York (1998-2006), mtDNAcn was measured in cord blood. Children (N = 336) were evaluated for their height, weight, and bioimpedance at age 5, 7, 9, and 11 years.
Article Synopsis
- - This study explores how growth patterns during puberty relate to future health outcomes by analyzing height data from about 56,000 individuals across various ancestries using a technique called SITAR.
- - The researchers identified 26 significant genetic loci linked to height growth during puberty and found that different growth rates are associated with various health risks, like type 2 diabetes and heart conditions.
- - The findings suggest that there are multiple growth trajectories during puberty, each influencing adult health differently, indicating that no single growth pattern is the "best" for lifelong health outcomes.
Background: Body composition assessment aids evaluation of energy stores and the impact of diseases and interventions on child growth. Current United States pediatric reference ranges from the National Health and Nutrition Examination Survey (NHANES) include 20% of children with obesity, body mass index of ≥95th percentile.
Objectives: This study aimed to develop dual energy X-ray absorptiometry (DXA) based reference ranges in a diverse cohort with low-obesity prevalence from the Bone Mineral Density in Childhood Study (BMDCS).