Publications by authors named "S Obaro"
Article Synopsis
- The study investigates the prevalence of rectovaginal group B Streptococcus (GBS) colonization in pregnant women during labor and its transmission to newborns in selected low-income and middle-income African and South Asian countries.
- Conducted across 11 maternity and obstetric facilities, the research involved collecting samples from 6,514 HIV-negative pregnant women at least 37 weeks gestation to analyze GBS culture and serotyping.
- The findings revealed a 24.1% rate of maternal GBS colonization, with the highest prevalence in Mali (41.1%) and the lowest in Ethiopia (11.6%), highlighting significant regional variations in GBS rates among pregnant women.
Low levels of vitamin D in maternal and cord blood have been associated with neonatal sepsis. This study assessed the association of vitamin D metabolites (25(OH)D, 3-epi-25(OH)D, and 24,25(OH)D) levels in maternal and cord blood with newborn sepsis evaluation in Nigerian mother-infant dyads. Maternal and cord blood from 534 mothers and 536 newborns were processed using liquid chromatography-tandem mass spectrometry.
View Article and Find Full Text PDFAntimicrobial peptide amphiphiles (PAs) are a promising class of molecules that can disrupt the bacterial membrane or act as drug nanocarriers. In this study, we prepared 33 PAs to establish supramolecular structure-activity relationships. We studied the morphology and activity of the nanostructures against different Gram-positive and Gram-negative bacterial strains (such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii).
View Article and Find Full Text PDFInvasive non-typhoidal Salmonella (iNTS) disease manifesting as bloodstream infection with high mortality is responsible for a huge public health burden in sub-Saharan Africa. Salmonella enterica serovar Typhimurium (S. Typhimurium) is the main cause of iNTS disease in Africa.
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