Publications by authors named "S O Savvi"
Using the example of a clinical case, to present the management features of a patient with complete esophageal obliteration as a chemical burn result, the surgical intervention features in case of a non-standard situation during the operation, and the treatment results analyze. It was described a clinical case of 41-year-old patient with thoracic esophagus obliteration due to extended post-burn cicatricial esophageal stricture, dysphagia of IV degree in very severe general condition. Stamm-Senn-Kader's gastrostomy was performed as a first step of surgical treatment.
View Article and Find Full Text PDFObjective: The aim of the researce was the improvement of treatment results of patients with extended post-burn esophageal cicatricial strictures.
Patients And Methods: Materials and methods: The treatment results are presented for 102 patients which were divided into two groups. In 49 patients with extended post-burn esophageal cicatricial strictures of the main group modified esophagoplasty were performed.
SURGICAL TREATMENT OF BENING ESOPHAGEAL STRICTURES AFTER CORROSIVE INJURIES.
Georgian Med News
May 2018
The research is based on the results of the examination and treatment of 156 patients who received treatment for extended benign esophageal strictures after corrosive injuries in the department of diseases of the esophagus and the gastrointestinal tract of the State Institution "V. T. Zaitsev Institute of General and Urgent Surgery of NAMS of Ukraine" for the period from 2000 to 2016.
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- The FANTOM5 project mapped transcription initiation events in human and mouse genomes with high precision using CAGE technology and single-molecule sequencing.
- Over 3,000 diverse samples, including primary cells and tissues, were analyzed through a standardized process starting from RNA quality assessment to generating transcription initiation frequencies.
- The analysis identified around 200,000 (human) and 150,000 (mouse) non-overlapping peaks, enabling the annotation of both known and novel promoters and providing insights into transcriptional regulation in different cellular states.
Classical activation of macrophages (caMph or M1) is crucial for host protection against Mycobacterium tuberculosis (Mtb) infection. Evidence suggests that IL-4/IL-13 alternatively activated macrophages (aaMph or M2) are exploited by Mtb to divert microbicidal functions of caMph. To define the functions of M2 macrophages during tuberculosis (TB), we infected mice deficient for IL-4 receptor α on macrophages (LysMcreIL-4Rα-/lox) with Mtb.
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