Grape seed oil attenuates sodium arsenite-induced gastric, hepatic and colonic damage in Wistar rats.

Arsenic exposure is associated with numerous morbidities due to dysfunction of various organ systems including the gastrointestinal tract. We investigated the protective effect of grape seed oil (GSO) against sodium arsenite (NaAsO)-induced gastric, hepatic and colonic injuries in rats. Twenty-four male Wistar rats were divided into four groups of six as follows: Group A (control) received saline; group B received NaAsO (2.

Supplementation with sesame oil suppresses genotoxicity, hepatotoxicity and enterotoxicity induced by sodium arsenite in rats.

Background: Sesame oil, an edible essential oil, is known to be rich in unsaturated fatty acids, vitamins and lignans with several reported health-promoting benefits. Acute arsenic poisoning produces toxic hepatitis, bone marrow depression and adverse gastrointestinal responses. In this study, we investigated the protective effect of sesame seed oil (SSO) against genotoxicity, hepatotoxicity and colonic toxicity induced by sodium arsenite (SA) in Wistar rats.

Chemometric analysis of ecological toxicants in petrochemical and industrial environments.

The application of chemometrics in the assessment of toxicants, such as heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) potentially derived from petrochemical activities in the microenvironment, is vital in providing safeguards for human health of children and adults residing around petrochemical industrial regions. Several multivariate statistical methods are used in geosciences and environmental protection studies to classify, identify and group prevalent pollutants with regard to exhibited trends. Chemometrics can be applied for toxicant source identification, estimation of contaminants contributions to the toxicity of sites of interest, the assessment of the integral risk index of an area and provision of mitigating measures that limit or eliminate the contaminants identified.

Redesigning the MCAT exam: balancing multiple perspectives.

The authors of this commentary discuss the recently completed review of the current Medical College Admission Test (MCAT), which has been used since 1991, and describe the blueprint for the new test that will be introduced in 2015. The design of the MCAT exam reflects changes in medical education, medical science, health care delivery, and the needs of the populations served by graduates of U.S.

Potential risk effect from elevated levels of soil heavy metals on human health in the Niger delta.

An analysis of the soil quality in the Niger Delta Area (NDA) was carried out to determine the severity of soil contamination. The United States Environmental Protection Agency (US EPA) risk assessment model was used in determining the potential health risk due to lifetime exposure (by means of ingestion, dermal contact and inhalation) of the population to heavy metal contents in the soil. Substantial levels of contamination were found indicating elevated levels of heavy metals above background concentrations from controlled samples in the areas.