Publications by authors named "S O Osipova"
The improvement of phenotyping methods is necessary for large-scale screening studies of wheat ( L.) drought tolerance. The objective of our research was to find out whether it is possible to use chlorophyll (Chl) fluorescence parameters instead of biochemical indicators of drought tolerance when screening wheat.
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- The study investigates the unclear causes of chronic obstructive pulmonary disease (COPD) and its potential link to chronic pulmonary aspergillosis (CPA).
- The prevalence of CPA was significantly higher in COPD patients than in those without COPD and healthy controls, indicating a potential relationship.
- It suggests that elevated levels of Interleukin-1β and tumor necrosis factor α in patients with ascariasis may raise the risk of CPA in COPD patients.
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- Antipsychotic medications can cause adverse drug reactions (ADRs), which remain a significant issue in psychiatry despite advancements in new APs.
- Research has identified genetic factors that influence drug transport across the blood-brain barrier, particularly focusing on specific transporter proteins like P-gp, BCRP, and MRP1 in patients with schizophrenia.
- The authors propose a pharmacogenetic test called PTAP-PGx to assess genetic variations affecting drug transport, along with a risk assessment tool and decision-making guidelines to help psychiatrists better manage these ADRs.
The World Health Organization reports that approximately 200 million people are infected with Giardia (G.) lamblia worldwide. Taking into account the emergence of resistance and the high toxicity of conventional drugs, research into new strategies to fight against G.
View Article and Find Full Text PDFDoxorubicin, which is widely used to treat a broad spectrum of malignancies, has pronounced dose-dependent side effects leading to chronic heart failure development. Nicotinamide riboside (NR) is one of the promising candidates for leveling the cardiotoxic effect. In the present work, we performed a comparative study of the cardioprotective and therapeutic actions of various intravenous NR administration modes in chronic doxorubicin-induced cardiomyopathy in Wistar rats.
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