External Factors Influencing the Motivation and Performance of Staff in Their Nutritional Work With Adults With Intellectual Disabilities.

Background: Staff working in municipal care homes with adults with intellectual disabilities impact their diet significantly.

Aim: To explore how external factors influence staff's motivation and performance of nutritional work with these residents.

Method: Semi-structured qualitative interviews with 11 staff using systematic text condensation for analysis.

Weight reduction and dietary improvements in a cluster-randomised controlled trial for adults with intellectual disabilities.

Background: People with intellectual disabilities (IDs) have an increased risk of obesity and health concerns related to their nutritional status and dietary intake.

Objective: To assess the effectiveness of a multi-component intervention on weight, waist circumference (WC), clinical health parameters and dietary habits in a group of overweight and obese adults with mild-to-moderate ID.

Design: A 7-month cluster-randomised trial and a 7-month follow-up of the intervention group after the end of intervention when the group received usual care.

Characterization of wooden breast myopathy: a focus on syndecans and ECM remodeling.

The skeletal muscle deformity of commercial chickens , known as the wooden breast (WB), is associated with fibrotic myopathy of unknown etiology. For future breeding strategies and genetic improvements, it is essential to identify the molecular mechanisms underlying the phenotype. The pathophysiological hallmarks of WB include severe skeletal muscle fibrosis, inflammation, myofiber necrosis, and multifocal degeneration of muscle tissue.

Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice.

Perilipin 2 (Plin2) binds to the surface of hepatic lipid droplets (LDs) with expression levels that correlate with triacylglyceride (TAG) content. We investigated if Plin2 is important for hepatic LD storage in fasted or high-fat diet-induced obese Plin2 and Plin2 mice. Plin2 mice had comparable body weights, metabolic phenotype, glucose tolerance, and circulating TAG and total cholesterol levels compared with Plin2 mice, regardless of the dietary regime.

Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue.

Proteoglycans are central components of the extracellular matrix (ECM) and binding partners for inflammatory chemokines. Morphological differences in the ECM and increased inflammation are prominent features of the white adipose tissues in patients with obesity. The impact of obesity and weight loss on the expression of specific proteoglycans in adipose tissue is not well known.