Publications by authors named "S O Emdin"
Background: The implementation of screening programmes in Sweden during the mid-1990s increased the number of small node-negative breast cancers. In this era before staging by sentinel node biopsy, routine axillary dissection for staging of early breast cancer was questioned owing to the increased morbidity and lack of perceived benefit. The long-term risk of axillary recurrence when axillary staging is omitted remains unclear.
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- A study showed that adding radiation therapy (RT) after breast surgery for a type of cancer called DCIS can lower the chances of getting breast cancer again by about 50% over 20 years.
- The researchers looked at over 1,000 women and found that those who got radiation had fewer cancer events than those who didn’t, especially for early-stage cancers.
- However, while RT helps reduce some cancer risks, it might cause other problems, like a slightly higher chance of cancer in the other breast, meaning doctors need to carefully decide who really needs RT.
Background: In a retrospective study on node-negative breast cancer, a prognostic index consisting of a proliferation factor, S-phase fraction (SPF), progesterone receptor status (PR), and tumour size identified one-third of patients as high risk, with a sixfold increased risk of breast cancer death. This prospective multicenter cohort study was set up to validate the index.
Patients And Methods: In 576 T1-2N0 patients <60 years, prospective analyses of PR and SPF were carried out.
Background: We studied the association between mammographic calcifications and local recurrence in the ipsilateral breast.
Methods: Case-cohort study within a randomised trial of radiotherapy in breast conservation for ductal cancer in situ of the breast (SweDCIS). We studied mammograms from cases with an ipsilateral breast event (IBE) and from a subcohort randomly sampled at baseline.
Purpose: Evaluate the effects of radiotherapy after sector resection for ductal carcinoma in situ of the breast (DCIS) in patient groups as defined by age, size of the lesion, focality, completeness of excision and mode of detection.
Patients And Methods: A total of 1,067 women in Sweden were randomly assigned to either postoperative radiotherapy (RT) or control from 1987 to 1999, and 1,046 were followed for a mean of 8 years. The main outcome was new ipsilateral breast cancer events and distant metastasis-free survival analyzed according to intention to treat.