Publications by authors named "S O Asagba"

Most research has not been done on the possible relationship between pregnant women's cross-metal exposures and postpartum neuroendocrine functions. The purpose of this study was to look into how co-exposure to aluminium chloride (AlCl) and cadmium chloride (CdCl) affected the neuroendocrine and neurometabolic changes in postpartum mice. A total of 24 adult pregnant female mice were used for the study.

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The current study comprised four groups of pregnant animals viz; Control (CTR) received 10 ml/kg of normal saline, Al:10 mg/kg of AlCl, Cd: 1.5 mg/Kg of CdCl Al+Cd; 10 mg/kg of AlCl and 1.5 mg/Kg of CdCl.

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There is limited experimental evidence on the biochemical consequences of aluminium (Al) and cadmium (Cd) co-exposures during pregnancy and postnatal life.This study investigated the impacts of perinatal Al chloride (AlCl) and Cd chloride (CdCl) co-exposures on neuroendocrine functions in mice offspring during postnatal life. The study comprised of four pregnant experimental groups.

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Article Synopsis
  • - This study investigated the health risks associated with long-term exposure to water contaminated with nickel (Ni) and cadmium (Cd) in male Wistar rats, using a structured experimental design that tested different doses and exposure durations.
  • - Results indicated that the exposure led to liver and kidney damage, evidenced by increased levels of certain enzymes (AST and ALT) and waste products (creatinine and blood urea nitrogen), which pointed to potential liver cirrhosis and renal dysfunction.
  • - The study also created multiple predictive models to analyze the effects of contamination on the rats, confirming that the pollutants caused significant oxidative stress and impaired antioxidant activity in liver and kidney tissues.
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The contamination of the aquatic ecosystem beyond tolerable limits may pose serious health challenges to its components. This study evaluated the toxic effects of a binary mixture of lead (Pb) and zinc (Zn) compounds on the activity of Na/K-ATPase in tissues of Clarias gariepinus in a controlled aquatic system. The study employed Box-Behnken Design (BBD) with 17 runs in which Pb and Zn concentrations were considered process variables in a time-dependent fashion.

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