Perinatal asphyxia in a rural Nigerian hospital: Incidence and determinants of early outcome.

Background: Perinatal asphyxia is an important cause of morbidity and mortality in the neonatal period, accounting for 20-30% of neonatal mortality. A substantial proportion (estimated at 26%) of the 1 million annual intrapartum stillbirths result from asphyxia. Probably higher than the mortality is the plethora of morbidity associated with asphyxia, especially long term neuro-developmental problems including cerebral palsy.

Suspected progeria in Nigeria: a case report.

Background: Progeria is a rare fatal genetic condition characterized by an appearance of accelerated aging in children. It has an incidence of 1 in 8 million and results from a mutation of the LMNA gene causing nuclear instability. Clinical diagnosis is based on recognition of common clinical features and definitive diagnosis is by identifying the mutation in the LMNA gene.

Molecular diagnostics for lassa fever at Irrua specialist teaching hospital, Nigeria: lessons learnt from two years of laboratory operation.

Background: Lassa fever is a viral hemorrhagic fever endemic in West Africa. However, none of the hospitals in the endemic areas of Nigeria has the capacity to perform Lassa virus diagnostics. Case identification and management solely relies on non-specific clinical criteria.

Computed tomography study of complicated bacterial meningitis.

Objective: To monitor the structural intracranial complications of bacterial meningitis using computed tomography (CT) scan.

Design: Retrospective study of medical and radiological records of patients who underwent CT scan over a 4 year period.

Setting: A University Teaching Hospital in a developing country.