Clinical and radiographic assessment of effect of platelet-rich fibrin on dental implant osseointegration - A split mouth randomized clinical trial.

Purpose: Biomimetic agents are being researched for their potential to stimulate bone formation and boost bone-implant contact. The objective of this study was to assess how osseointegration of dental implants is impacted by platelet-rich fibrin.

Materials And Methods: The present study was a randomized clinical trial with a split mouth design.

In Vitro Comparison of Polymerization Techniques on the Strength and Hardness of Denture Base Resins.

Purpose: Acrylic dentures fabricated using polymethyl methacrylate are subjected to either intraoral fatigue stress or extraoral impact stress, eventually forming microcracks and fractures. This limitation should be overcome by either modification in the acrylic resin material or in polymerization techniques. This study compares the impact strength and flexural strength of high-impact resin to conventional resin in short- and long-heat polymerization settings.

An Enhanced Scrutiny of Mechanistic and Translational Approaches to Extinguish Cancer Hypoxia.

Cancer continues to pose a formidable challenge in global health due to its incidence and increasing resistance to conventional therapies. A key factor driving this resistance is tumor hypoxia, characterized by reduced oxygen levels within cancer cells. This hypoxic environment triggers a variety of adaptive mechanisms, significantly compromising the efficacy of cancer treatments.

Molecular dynamics simulation studies on RbgA: insights into the RbgA-ribosome association and GTPase activity.

RbgA (ribosome biogenesis GTPase A) is involved in the maturation of later stages of the 50S ribosomal subunit by associating with the 45S ribosomal subunit. However, this binding relies on the specific nucleotide-bound state of RbgA-GTP-bound state is more favorable compared GDP-bound state, attributed to the conformational variations between those states. Therefore, to explore the conformational changes of RbgA, all-atom MD simulations of RbgA were carried out under various nucleotide bound states (GDP, GTP, GTP-Mg and GMPPNP-Mg).

Comparative investigation of structural properties and biological applications of chemical and biogenic synthesis of zirconium dioxide (ZrO) nanoparticles using Passiflora edulis.

Over the last decade, the environmental and wellness cost of antibiotic drug resistance to the societies have been astounding and require urgent attention Metal oxide nanomaterials have been achieved a pull-on deal with its entire applications in biological and photocatalytic applications. The present study conducts a comparative investigation on chemical and biogenic synthesis of zirconium dioxide (ZrO) nanoparticles aimed at enhancing their efficacy in their applications. The plant extract of Passiflora edulis act as a reducing and capping properties offering a sustainable and eco-friendly alternative.