Publications by authors named "S Numoto"

Article Synopsis
  • Subependymal giant cell astrocytoma (SEGA) occurs in 5-20% of patients with tuberous sclerosis complex (TSC) and can lead to complications like hydrocephalus.
  • A 14-year-old boy with TSC developed SEGA and hydrocephalus, with treatments reducing tumor size but not resolving ventricular enlargement.
  • The situation emphasizes the importance of considering multiple factors affecting cerebrospinal fluid (CSF) dynamics, and highlights the need for improved treatment strategies in TSC patients with SEGA.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to analyze diffusion-weighted imaging (DWI) findings in young children with moyamoya disease (MMD) during the early stages of the condition.
  • Data was collected from 12 children under six years old, showing various DWI abnormalities primarily affecting the cerebral cortex, with distinct lesion types identified.
  • Surprisingly, all children had internal carotid artery stenosis, but the severity did not always correlate with the ischemic lesions observed, indicating unique patterns of injury in MMD compared to typical strokes.
View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates how cavernous malformations (CM) can lead to epilepsy, particularly focusing on cases where the seizure onset location doesn't match findings from scalp EEG, known as false lateralization (FL).
  • - Analyzed 32 patients with CM-associated epilepsy, finding FL in about 10% of cases for interictal and ictal discharges, and those with FL had a significantly higher occurrence of CM located in medial and deep brain areas.
  • - The research suggests that neurologists should be cautious when deciding on surgical resection areas based solely on EEG results, especially in cases with deep and medial CM, as they can present misleading information.
View Article and Find Full Text PDF

Background: Traditional brain activity monitoring via scalp electroencephalography (EEG) offers limited resolution and is susceptible to artifacts. Endovascular electroencephalography (eEEG) emerged in the 1990s. Despite early successes and potential for detecting epileptiform activity, eEEG has remained clinically unutilized.

View Article and Find Full Text PDF
Article Synopsis
  • - Biliary atresia (BA) is a rare condition in infants that leads to jaundice and can cause vitamin K deficiency bleeding (VKDB), leading to complications such as hematomas from vaccinations.
  • - A case of an 82-day-old girl with BA developed a significant hematoma in her arm after receiving a pneumococcal vaccine, resulting in a radial nerve palsy due to the bleeding.
  • - Timely detection and management of BA and VKDB are crucial, as delays can lead to severe consequences, including lasting nerve damage even after treatment interventions like liver transplant.
View Article and Find Full Text PDF