Publications by authors named "S Nouveau"
Article Synopsis
- Age acceleration/deceleration (Age A/D) can be assessed through various clinical measurements of skin conditions, which may not align with a person's chronological age.
- A study involving 360 women identified three distinct skin classes based on attributes like dryness, elasticity, and oiliness, and examined how these related to the levels of specific proteins in the skin.
- The research highlighted that higher levels of insulin degrading enzyme (IDE) in the stratum corneum are linked to slower skin aging, suggesting that molecular markers could help predict age-related skin changes.
Actinic lentigines (AL) or age spots, are skin hyperpigmented lesions associated with age and chronic sun exposure. To better understand the physiopathology of AL, we have characterized the inflammation response in AL of European and Japanese volunteers. Gene expression profile showed that in both populations, 10% of the modulated genes in AL versus adjacent non lesional skin (NL), i.
View Article and Find Full Text PDFBackground: Solar light induces or aggravates hyperpigmentation issues. The contribution of UVA1, as well as visible light (VL), especially high-energy blue-violet visible (HEV) light, is now clearly established.
Objectives: This work aimed at determining the relative contribution of UVA1, HEV and VL wavelength bands and their sub-domains in pigmentation induction.
Background: Hyperpigmented spots develop earlier and with a higher incidence in Asian individuals compared with Europeans. Although actinic lentigines (AL) are very common, the biological events underlying their formation remain ill-defined.
Objective: AL from Japanese volunteers were characterized through morphological and gene expression analyses.
Purpose: Assessing the percutaneous absorption of cosmetic ingredients using in-vitro human skin reveals certain limitations, such as restricted anatomical sites and repeated exposure, and to overcome these issues, in-vivo studies are required. The aim of the study is to develop a robust non-invasive in-vivo protocol that should be applicable to a wide range of application.
Methods: A robust tape stripping protocol was therefore designed according to recent recommendations, and the impact of two different washing procedures on caffeine distribution in tape strips was investigated to optimise the protocol.