Publications by authors named "S Noorani"
The synthesis of ()-1-(1,3-diphenylallyl)-1-1,2,4-triazoles and related compounds as anti-mitotic agents with activity in breast cancer was investigated. These compounds were designed as hybrids of the microtubule-targeting chalcones, indanones, and the aromatase inhibitor letrozole. : A panel of 29 compounds was synthesized and examined by a preliminary screening in estrogen receptor (ER) and progesterone receptor (PR)-positive MCF-7 breast cancer cells together with cell cycle analysis and tubulin polymerization inhibition.
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- A lot of pregnant women around the world have a health problem called anemia, which is especially common in low-income places like rural Pakistan.
- In a study in Karachi, midwives helped treat anemia with IV iron therapy, and a lot of women showed improvement after the treatment.
- The study showed that many women moved from being very anemic to healthier levels after receiving this special care, which suggests that this midwife-led approach can really help pregnant women.
Depression is a serious mental health disorder affecting millions of individuals worldwide. Timely and precise recognition of depression is vital for appropriate mediation and effective treatment. Electroencephalography (EEG) has surfaced as a promising tool for inspecting the neural correlates of depression and therefore, has the potential to contribute to the diagnosis of depression effectively.
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- Scientists are studying how to make more of the healthy part of the liver before surgery, which is important for patients with liver issues.
- They used a special MRI test to check the condition of the liver in 10 patients before and after a procedure called dual vein embolization (DVE).
- After the DVE, the patients showed better liver health and increased healthy liver volume, which helps in avoiding problems during major liver surgery.
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- Hereditary angioedema (HAE) is a rare genetic disorder leading to recurrent swelling, which can be life-threatening, and its treatment includes both on-demand and preventive options.
- The last UK consensus on HAE was in 2014, but new medications have emerged, and there's a call for long-term prophylaxis (LTP) to effectively manage the condition and enhance patient quality of life.
- A recent Delphi process revealed that current UK access criteria for LTP based solely on attack frequency are too simplistic and may overlook patients who could benefit, emphasizing the need for expert care and improved monitoring practices.