Publications by authors named "S Niwano"

Background: Catheter ablation (CA) can improve exercise tolerance and quality of life (QOL) in patients with atrial fibrillation (AF). However, its differential effects on muscle strength between paroxysmal AF (PAF) and nonparoxysmal AF (Non-PAF) remain unclear.

Methods: We evaluated 94 patients (67.

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Article Synopsis
  • The study aimed to investigate the long-term impacts of the drug febuxostat on arterial stiffness in patients with high uric acid levels, with a particular focus on liver function.
  • In the PRIZE study, patients were randomly assigned to either receive febuxostat or non-drug treatments, with assessments of arterial stiffness conducted at 12 and 24 months.
  • While overall changes in arterial stiffness were not significantly different between the two groups, those with elevated liver enzyme levels showed notable improvements after 24 months of febuxostat treatment.
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Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death with type 2 diabetes; however, their effect on arrhythmias is unclear. The purpose of this study was to investigate the effects of empagliflozin on ventricular arrhythmias in patients with type 2 diabetes.

Methods: A total of 150 patients with type 2 diabetes who were treated with an implantable cardioverter-defibrillator or cardiac resynchronization therapy defibrillator (ICD/CRT-D) were randomized to once-daily empagliflozin or placebo for 24 weeks.

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Background: Novel diamond-embedded catheter enables precise temperature-controlled ablation. However, the effects of contact angle on lesion formation of this catheter are poorly understood.

Objective: The purpose of this study was to evaluate lesion formation using the temperature-controlled ablation catheter embedded with diamond at different angles in a porcine experimental model.

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