Publications by authors named "S Nishiguchi"

The adhesive function of cell surface proteins can be visually assessed through direct observation; however, the underlying structures that mediate adhesion typically remain invisible at the nanoscale level. This hinders knowledge on the diversity of molecular architectures responsible for cell-cell adhesion. Drosophila E-cadherin (DE-cadherin), a classical cadherin with a unique domain structure, demonstrates adhesive function; however, it lacks a structural model that explains its adhesion mechanism.

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  • Resident physicians in Japan were expected to care for COVID-19 patients, but many faced burnout, with limited studies on their experiences and competency gains in this context.
  • A national study involving over 6,000 resident physicians assessed their training and COVID-19 care experience using the General Medicine In-Training Examination to measure competency.
  • Results indicated that while many residents had no COVID-19 care experience, those who did performed better on COVID-19-related questions, suggesting that this experience positively impacted their competency without hindering their fundamental clinical skills.
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  • Autoimmune neuromuscular disorders like myasthenia gravis (MG) are rare in patients with eosinophilic granulomatosis with polyangiitis (EGPA).
  • Two previous cases of MG alongside EGPA were reported, but in those instances, EGPA occurred years after starting MG treatment.
  • A 75-year-old man is described who had both EGPA and MG simultaneously, and he was successfully treated with immunosuppressive therapy; it's important to differentiate symptoms of each condition in patients with eosinophilia.
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We report 16S rRNA gene amplicon data on the succession of intestinal microbiomes in migratory bird, Eurasian Wigeon (Mareca Penelope) wintering around Osaka, Japan. This study could serve as baseline data for comparison with microbiomes in migratory birds.

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Background: The relationship between educational outcomes and the use of web-based clinical knowledge support systems in teaching hospitals remains unknown in Japan. A previous study on this topic could have been affected by recall bias because of the use of a self-reported questionnaire.

Objective: We aimed to explore the relationship between the use of the Wolters Kluwer UpToDate clinical knowledge support system in teaching hospitals and residents' General Medicine In-Training Examination (GM-ITE) scores.

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